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Subject:
From:
Nikki Lee <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 1 Jul 2011 16:37:49 -0400
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Dear Lactnet Friends:

Can't test genetically engineered food in humans. So use rats for 90 days.
The new food contains a version of human lactoferrin that is in the milk of
transgenically engineered cows. Rats are still alive, therefore the food
must be safe for humans.

Maybe this should be tested in politicians, the closest thing to rats I can
think of?

Drug Chem Toxicol. <http://www.ncbi.nlm.nih.gov/pubmed/21714769#> 2011 Jun
30. [Epub ahead of print]
A 90-day safety study in Sprague-Dawley rats fed milk powder containing
recombinant human lactoferrin (rhLF) derived from transgenic cloned cattle.
Zhou C <http://www.ncbi.nlm.nih.gov/pubmed?term=%22Zhou%20C%22%5BAuthor%5D>
, Wang JW<http://www.ncbi.nlm.nih.gov/pubmed?term=%22Wang%20JW%22%5BAuthor%5D>
, Huang KL<http://www.ncbi.nlm.nih.gov/pubmed?term=%22Huang%20KL%22%5BAuthor%5D>
, He X <http://www.ncbi.nlm.nih.gov/pubmed?term=%22He%20X%22%5BAuthor%5D>, Chen
XP <http://www.ncbi.nlm.nih.gov/pubmed?term=%22Chen%20XP%22%5BAuthor%5D>, Sun
H <http://www.ncbi.nlm.nih.gov/pubmed?term=%22Sun%20H%22%5BAuthor%5D>,
Yu T<http://www.ncbi.nlm.nih.gov/pubmed?term=%22Yu%20T%22%5BAuthor%5D>
, Che HL<http://www.ncbi.nlm.nih.gov/pubmed?term=%22Che%20HL%22%5BAuthor%5D>
.
 Source

College of Food Science and Nutritional Engineering, China Agricultural
University , Beijing , China.
Abstract

Transgenic cloned animals expressing beneficial human nutritional traits
offer a new strategy for large-scale production of some kinds of functional
substances. In some cases, the required safety testing for genetically
modified (GM) foods do not seem appropriate for human food safety, though
regulations do not seem to provide alternatives. A 90-day rat feeding study
is the core study for the safety assessment of GM foods.


The test material in this 90-day study was prepared nonfat milk powder
containing recombinant human lactoferrin (rhLF), which was expressed in
transgenic cloned cattle. Groups of 10 male and female Sprague-Dawley rats
were given a nutritionally balanced purified diet containing 7.5, 15, or 30%
transgenic or conventional milk powder for 90 days. A commercial AIN93G diet
was used as an additional control group.


Clinical, biological, and pathological parameters were compared between
groups. The only significant effect of treatment was higher mean ferritin
and Fe(+) concentrations for both male and female rats fed the transgenic
milk powder diets, as compared to rats fed nontransgenic milk diets or the
commercial diet.


The results of the present study are consistent with previous research,
which indicates that milk powder containing rhLF derived from healthy
transgenic cloned cattle is as safe as conventional milk powder.

warmly
Nikki Lee RN, BSN, Mother of 2, MS, IBCLC, CCE, CIMI, ANLC, CKC
craniosacral therapy practitioner
www.breastfeedingalwaysbest.com

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