How do you know that there is no cow's colostrum with human milk proteins
being marketed?  What proof can you offer me that it is not a done deed?  FDA
regulation?  I am laughing.  I see all these patents and companies forming to
market lactoferrin and I am suppose to believe that it hasn't
happened--particularly when the FDA refused to answer any more of my
questions and referred me to FOIA (Freedom of Information Act).


As for DHA--patent 5397591 which was filed in 1992 and approved in 1995--it
specifies that recombinant organisms are part of this patent.  Now since the
patent was filed in 1992, am I to believe that this has not happened yet?
This is a patent from Martek Biotechnology Inc. and as far as I know they are
still in business selling DHA to formula companies in Europe and Asia and
supplements to everybody.

you have to go to the patent office on the web site
http://www.uspto.gov/patft/index.html

Any microorganisms capable of producing a single-cell edible oil containing
DHA can be used in the present invention. For example, photosynthetic diatoms
can be used. Preferred microorganisms are marine dinoflagellates, including
Crypthecodinium sp. Especially preferred is Crypthecodinium cohnii, an
obligate heterotroph requiring a reduced carbon source for growth. C. cohnii
is preferred because it contains a fatty acid profile in which DHA is the
only PUFA present in sufficient quantities (greater than about 1% of the
total amount of PUFAs). Samples of this organism, designated MK8840, have
been deposited with the American Type Culture Collection at Rockville, Md.,
and assigned accession number 40750. As used herein, microorganism, or any
specific type of microorganism, includes wild strains, mutants or recombinant
types. Any microorganism which produces enhanced levels of oil containing DHA
is considered to be within the scope of this invention. One of the features
of the present invention is its recognition of the edible oil-producing
capability of microorganisms such as dinoflagellates and the attendant
solution to the problem of maintaining a reliable, economic source of such
oils. Accordingly, wild-type and recombinant microorganisms designed to
produce single cell oil containing DHA are an aspect of this invention. Such
recombinant organisms would include those designed to produce greater
quantities of DHA in the single cell oil, greater quantities of total oil, or
both, as compared to the quantities produced by the same wild type
microorganism, when provided with the same substrates. Also included would be
microorganisms designed to efficiently use more cost-effective substrates
while producing the same amount of single cell oil containing DHA as the
comparable wild-type microorganism."

--Valerie W. McClain, IBCLC

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