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Subject:
From:
"Valerie W. McClain, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 30 Oct 2000 12:10:04 EST
Content-Type:
text/plain
Parts/Attachments:
text/plain (222 lines)
Kathy D., You admit to not catching the beginning of this discussion and yet
you quickly write that I have no credibility because I have not cited my
sources of information.  Over and over again I have cited sources.  I
actually posted a correction to my one of my last posts with the web site
where the abstract on the modification of grains was posted.  No it never
stated oats and I never said oats (not oatmeal) were genetically modified.
Although I did say I suspected oats were because all the other grains were
being used. The major discussion is the genetic engineering of human milk
components to be used in infant formula and in pharmaceuticals.  This is a
patent (one of about 200--I hope that you don't want me to post them all).
It was filed in September 1991 and approved in February 2000.  Valerie W.
McClain, IBCLC


You will have to go to the US Patent Office
http://www.uspto.gov/patft/index.html

do a number search---6020015 to see the whole patent.

United States Patent  6,020,015
Gaull  February 1, 2000

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Infant formula compositions and nutrition containing genetically engineered
human milk proteins


Abstract
Compositions containing human milk proteins, including the so-called host
resistance factors of human milk, prepared by chemically synthesizing the
human milk proteins or by genetic engineering techniques for producing
recombinant human milk proteins, are useful for supplementing or enhancing
the diet of infants, particularly very-low-birth-weight infants. The human
milk proteins include the host resistance factors (HRF) found in human milk,
such as lactoferrin (LF), lactoperoxidase (LP), lysozyme (LZ),
immunoglobulin-A (IgA), alpha-lactalbumin, alpha, beta, kappa-caseins, and
others. The compositions may also include components other than the human
milk proteins useful for improved infant nutrition. In the utilization of the
compositions of this invention, the compositions would be administered to an
infant in at least an amount that the infant would receive if fed
substantially only fresh human milk. Also, the proportions of the human milk
proteins would preferably be present in the compositions in about the
proportions these proteins are found in human milk.


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Inventors:  Gaull; Gerald E. (2949 Harrison St., Evanston, IL 60201)
Appl. No.:  759100
Filed:  September 6, 1991

Current U.S. Class: 426/580; 426/72; 426/74; 426/801; 435/192; 435/206;
530/360; 530/365
Intern'l Class:  A23C 009/00
Field of Search:  426/72,74,580,801 530/387,365,360 435/192,206



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References Cited [Referenced By]

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U.S. Patent Documents
4112123 Sep., 1978 Roberts 426/74.
4216236 Aug., 1980 Mueller et al. 426/801.
4303692 Dec., 1981 Gaull 426/580.
4419369 Dec., 1983 Nichols et al. 426/2.
4497836 Feb., 1985 Marquadt 426/239.
4519821 May., 1985 Palmiter 435/172.
4617190 Oct., 1986 Montgomery 426/61.
4670268 Jun., 1987 Mahmoud et al. 426/72.
4670285 Jun., 1987 Clandinin et al. 426/602.
4753926 Jun., 1988 Lucas et al. 426/72.
4782138 Nov., 1988 Rialland et al. 426/543.
4977137 Dec., 1990 Nichols et al. 426/74.
5795611 Aug., 1998 Slattery 426/580.
Foreign Patent Documents
8511447 Jun., 1986 EP.
8830111 Feb., 1988 EP.
8022390 Feb., 1982 FR.
60-05892 Apr., 1985 JP.
8704050 Jul., 1987 WO.
880239 Jan., 1988 WO.
8801648 Aug., 1988 WO.
8810118 Dec., 1988 WO.



Other References
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159-169.
Raiha, N.C.R. 1985. "Nutritional Proteins in Milk and the Protein Requirement
of Normal Infants" in Pediatrics pp. 136-141.
Friend, B.A. 1983. "Newer Advances in Human Milk Substitutes for Infant
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Nutritional Consequences, Bellanti, J.A., ed. 1983, pp. 123-128.
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Systems in Milk--A Review", Microbiologie, 1984, 2:1-20.
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Milk Banking, A.F. Williams, eds., (Raven Press 1984), p. 93-100.
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in Human Milk Banking, A.F. Williams, ed., (Raven Press 1984), p. 123-132.
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Complexes," in Human Milk Banking, A.F. Williams, ed., (Raven Press 1984),
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Protein Requirements of Very-Low-Birth-Weight Infants," in Human Milk
Banking, A.F. Williams, ed., (Raven Press 1984), p. 159-170.
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Low-Birth-Weight Infants Fed with Banked Human Milk, Human Milk Formula, or
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Very-Low-Birth-Weight Infant: Discussion," in Human Milk Banking, A.F.
Williams, ed., (Raven Press 1984), p. 179-184.
Qasba et al, "Similarity of the nucleotide sequences of rat alpha-lactalbumin
and chicken lysozyme genes," Nature, Mar. 22, 1984, 308:377-380.
Swift et al, "Tissue-Specific Expression of the Rat Pancreatic Elastase I
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Agents," Biochem. Biophys. Acta, 1968, 170:351-365.
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Promotes Thymidine Uptake Into DNA of Rat Intestinal Crypt Cells,"
Gastroenterology and Nutrition, p. 273A.
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Decrease Mortality of Enterotoxigenic E. Coli (ETEC) Infection," Neonatal
Infections Diseases, p. 417A, No. 1464.
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Sep. 1963, vol. 25, No. 9, pp. 345-358.

Primary Examiner: Pratt; Helen
Attorney, Agent or Firm: McDonnell, Boehnen, Hulbert & Berghoff

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Parent Case Text

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This application is a continuation of application Ser. No. 07/247,981, filed
Sep. 22, 1988 now abandoned.
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