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Subject:
From:
"M. Young, BA, IBCLC, RLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 23 Jul 2003 12:24:01 -0400
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could some of the cases be undiagnosed H. Pylori infection?

Also, I found this abstract quite interesting. I'm wondering if the
abdominal distress in infants may be a function of their increased
vulnerability to some of these substances .....

Emerg Med Clin North Am. 1989 Aug;7(3):667-82.


Toxicologic causes of acute abdominal disorders.

Mueller PD, Benowitz NL.

San Francisco Regional Poison Control Center, University of California.

A variety of drugs and toxins can produce severe abdominal pain and, in
some cases, a surgical abdomen. Toxins can be classified according to
mechanisms of injury: 1. Corrosives often produce severe gastroenteritis
and may result in gastric or esophageal perforations. Examples of corrosive
substances include aspirin, iron, mercury, acids and alkali. 2. Drugs may
cause intestinal ileus or obstruction by pharmacologic actions (i.e.,
anticholinergic drugs and narcotics) or by mechanical obstruction (charcoal
and drug bezoars). 3. Abdominal pain simulating an acute abdomen may result
from systemic effects of black widow spider envenomation or intoxication
with heavy metals such as lead and arsenic. 4. Ischemic bowel disease may
occur from use of vasoconstrictor drugs, such as ergotamines, amphetamines
and cocaine, or may follow treatment with catecholamines or digitalis in
critically ill patients. Small bowel ischemia is life-threatening and may
require bowel resection. 5. Many drugs cause abdominal pain by directly
injuring abdominal organs, such as the liver and pancreas. Antibiotic-
associated colitis may present with abdominal pain and inflammatory
diarrhea. Consideration of drugs and toxins plays an important role in the
differential diagnosis of the acute abdomen.

Margaret
BC Canada

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