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Subject:
From:
"Jenny Thomas, MD, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 2 Aug 2006 09:39:11 -0400
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Hi there,

I'm a general pediatrician and I see lots of problems with milk supply in 
moms with PCOS.  Dr. Mona Gabbay presented an abtract at the Academy of 
Breastfeeding Medicine meeting a few years ago, that I think Dr. Lawrence 
references in her book, about a series of patients with PCOS who had low 
milk volume and responded, although with only mild increases in supply, 
with metformin.  These women were all about 6 week post-partum and she 
hypothesized that earlier initiation of metformin may have helped their 
supply.

I have worked with mothers with PCOS to try to continue their metformin 
throughout pregnancy and lactation and have seen that milk volumes that the 
moms have increased.  Some of these mothers have served as their own 
control-- they have achieved little breast changes and milk supply with 
their first pregnancy when the metformin was used to help them conceive and 
then discontnued after the first trimester, and with their next pregnancy, 
if we have been able to convince the OB/GYN to continue the metformin, the 
milk supply and reports of breast changes increased.  

Insulin is important at all levels of breast development and milk 
production, so I think it makes sense that insulin resistance would mess up 
those processes.

Hope that helps,

Jenny Thomas, MD, IBCLC

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