LACTNET Archives

Lactation Information and Discussion

LACTNET@COMMUNITY.LSOFT.COM

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
"Linda L. Pohl, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 27 Jun 2003 11:06:42 -0700
Content-Type:
text/plain
Parts/Attachments:
text/plain (54 lines)
Many people on Lactnet have touted the efficacy of Grapefruit Seed Extract
on yeast infection.  Most of the reports seem to be either anecdotal or
claims made by people selling the GSE.
A year or two ago I had heard that GSE was not effective, it was chemicals
added to the GSE that actually worked and unadulterated GSE itself had no
effect.  While looking further into it for a client, I came across the
article below on PubMed.  Does anyone have anything published in a peer
reviewed journal that would refute the conclusion that natural GSE without
additives have any antifungal effect.
Linda L Pohl, IBCLC, on a quest for evidence-based practice....
Phoenix AZ

Pharmazie. 1999 Jun;54(6):452-6.

Aspects of the antimicrobial efficacy of grapefruit seed extract and its
relation to preservative substances contained.

von Woedtke T, Schluter B, Pflegel P, Lindequist U, Julich WD.

Institute of Pharmacy, Ernst Moritz Arndt University, Greifswald, Germany.

The antimicrobial efficacy as well as the content of preservative agents of
six commercially available grapefruit seed extracts were examined. Five of
the six extracts showed a high growth inhibiting activity against the test
germs Bacillus subtilis SBUG 14, Micrococcus flavus SBUG 16, Staphylococcus
aureus SBUG 11, Serratia marcescens SBUG 9, Escherichia coli SBUG 17,
Proteus mirabilis SBUG 47, and Candida maltosa SBUG 700. In all of the
antimicrobial active grapefruit seed extracts, the preservative benzethonium
chloride was detected by thin layer chromatography. Additionally, three
extracts contained the preserving substances triclosan and methyl parabene.
In only one of the grapefruit seed extracts tested no preservative agent was
found. However, with this extract as well as with several self-made extracts
from seed and juiceless pulp of grapefruits (Citrus paradisi) no
antimicrobial activity could be detected (standard serial broth dilution
assay, agar diffusion test). Thus, it is concluded that the potent as well
as nearly universal antimicrobial activity being attributed to grapefruit
seed extract is merely due to the synthetic preservative agents contained
within. Natural products with antimicrobial activity do not appear to be
present.

PMID: 10399191 [PubMed - indexed for MEDLINE]

             ***********************************************

To temporarily stop your subscription: set lactnet nomail
To start it again: set lactnet mail (or digest)
To unsubscribe: unsubscribe lactnet
All commands go to [log in to unmask]

The LACTNET mailing list is powered by L-Soft's renowned
LISTSERV(R) list management software together with L-Soft's LSMTP(TM)
mailer for lightning fast mail delivery. For more information, go to:
http://www.lsoft.com/LISTSERV-powered.html

ATOM RSS1 RSS2