"Biological organization will never be understood except as the expression of an underlying evolutionary process." 

There is much more to understand about evolution than traits observed by naturalists in the field and base-by-base changes in DNA sequences observed in the laboratory. The genome is organized, with hierarchies of recognition and control. An evolutionary perspective is essential to comprehending this organization. 
  
In evolution, there would be a selective advantage for descendants of an individual that evolved an active framework that focuses exploration, compared to descendants of individuals that have a uniform probability of trying every mutation and every insertion site. 
 
Natural selection has led to the evolution, in genomes, of information that structures exploration and facilitates successful adaptation to likely challenges; thus, the most revealing and intriguing aspect of mutation, the generation of variation, is not that it is random, but rather the ways and extent to which it may become biased by feedback from selection.

SOURCE:
Caporale, L. H., & Doyle, J. (2013). In Darwinian evolution, feedback from natural selection leads to biased mutations. Annals of the New York Academy of Sciences.

             ***********************************************
The BEE-L mailing list is powered by L-Soft's renowned
LISTSERV(R) list management software.  For more information, go to:
http://www.lsoft.com/LISTSERV-powered.html