QUOTE MATERIAL for review purposes only

Propolis has attracted researchers’ interest in the last decades
because of several biological and pharmacological properties,
such as immunomodulatory, antitumor, antimicrobial, antiinflammatory,
antioxidant, among others (Bankova et al., 2000).

Propolis is safe and shows no side effect after administration.
Propolis shows antimicrobial activities, and its effects may occur
through a direct action on microorganisms and indirectly as well
via stimulation of the immune system and further microorganism
killing. Propolis may also show synergistic effects with antimicrobial
drugs. These data are promising but lack investigation

The knowledge of propolis mechanisms of action on the
immune system has advanced in the last years. In vitro and in vivo
assays demonstrated that propolis may activate macrophages,
increasing their microbicidal activity.

Propolis shows antitumor properties and its anticarcinogenic
and antimutagenic potential is promising, but the mechanisms
involved in the chemoprevention by propolis are still obscure.

Since humans have
been using propolis for a long time, scientific-based information
bring an important contribution, evidencing the necessity
of basic researches in this field and opening perspectives for
new works.

END QUOTE

Propolis and the immune system: a review, by J.M. Sforcin ∗
Journal of Ethnopharmacology 113 (2007)

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