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Informed Discussion of Beekeeping Issues and Bee Biology

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Subject:
From:
Peter L Borst <[log in to unmask]>
Reply To:
Informed Discussion of Beekeeping Issues and Bee Biology <[log in to unmask]>
Date:
Thu, 11 Jul 2013 08:05:55 -0400
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Hi all
You will probably be hearing a lot about sulfoxaflor. The action of sulfoxaflor was characterized at insect nicotinic acetylcholine receptors (nAChRs), but it is NOT a neonic. What this means is: banning the neonics as a class of insecticides will only drive researchers to develop new classes, such as the sulfoximines. 

> The novel sulfoxaflor-nAChR interaction is uniquely different than that of the neonicotinoids. The unique interaction of sulfoxaflor at the nAChR, in conjunction with its novel chemical structure, metabolic stability, and lack of cross-resistance suggest that sulfoxaflor will be an important new insecticide option for the control of sap-feeding insects. Sulfoxaflor is stable to mono- oxygenases that are known to readily metabolize other insecticides such as organochlorines and the neonicotinoids

 -- Watson et al (2011). Novel nicotinic action of the sulfoximine insecticide sulfoxaflor. Insect biochemistry and molecular biology, 41(7), 432-439.

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