Despite the fact that honey bees can harbor multiple
virus infections simultaneously, gaps still exist in
our current knowledge of the effects of such mixed infections
on pathogenic processes in honey bees. Whether
the viruses infect the same host but occupy separate
physiological niches in the bees or infect the bee and
share the same microenvironment to compete for host
resources remain to be determined. Moreover, it is not
known whether mixed virus infections could lead to genetic
recombination between coexisting viruses and
whether such recombination could result in the emergence
of new viruses.

-- 
"Multiple virus infections in the honey bee and
genome divergence of honey bee viruses"
Yanping Chen, Yan Zhaob, John Hammond,
Hei-ti Hsu, Jay Evans, Mark Feldlaufer
USDA

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