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EPA pesticide fact sheet for spirotetramat

http://www.epa.gov/opprd001/factsheets/spirotetramat.pdf

OPPTS Guideline 850.3040; Field Testing for Pollinators
Despite that the intrinsic hazard potential to bees based on the acute oral and
contact studies with honey bees appears to be low, brood feeding tests with
bees and acute toxicity contact studies with other non-target insects (e.g.
parasitoid wasps and predatory mites) conducted at less than the maximum
application rate suggest there is potential for mortality in adults and pupae,
massive perturbation of brood development, and early brood termination as a
result of spirotetramat use. This information, coupled with the fact that two
other chemicals representing the ketoenole class of compounds
(spiromesifen and spirodiclofen) have also demonstrated the potential for
chronic effects on bee broods and development while displaying low acute
toxicity, suggests that the mode of action of these compounds (i.e., inhibition
of lipid biosynthesis) may adversely affect bee broods and development.
Although a study has been submitted for spirotetramat under guideline
850.3040, it was conducted at application rates approximately half of the
label-recommended rates and it was not designed in such a manner that
adverse effects resulting from treatment could be statistically determined.
Therefore, it is recommended that a study design be developed in
collaboration with the Environmental Fate and Effects Division’s chemical
teams for spirotetramat, spiromesifen, and spirodiclofen, as well as with the
USDA Agricultural Research Service Bee Research Lab


End-Use Products:
This product is toxic to bees. Direct exposure to treatment or residues on blooming
crops or weeds can lead to effects on colonies. Do not apply this product or allow it
to drift if bees are visiting the treatment area.

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