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Informed Discussion of Beekeeping Issues and Bee Biology

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Subject:
From:
Peter L Borst <[log in to unmask]>
Reply To:
Informed Discussion of Beekeeping Issues and Bee Biology <[log in to unmask]>
Date:
Thu, 28 Oct 2010 16:09:51 -0400
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Bob writes:
>Give us the short version of what remebee is made of (ingredients) and the application method if you would.

The ingredient is synthetic RNA, which if fed to bees, produces a response which then targets a virus. It would be fed in sugar sirup.

RNA interference works by setting up an immune response to a particular virus. This is very similar to how vaccination works, except vaccines are normally made of actual viruses. RNA and DNA are simply long molecules that contain codes required by living things to function. If you introduce a small piece of code (synthetic RNA) into the animal, that code becomes a target and the RNA silencing mechanisms go after anything with that target, and shut them down.

"This specific strategy should be particularly useful for long-term RNAi gene therapies against persisting exogenous targets, such as HIV or hepatitis viruses" -- Dirk Grimm, Stanford University School of Medicine

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