>Please recall that the main point of the discussion was supposed to be
"how will adaptation to neonics develop?"

Yes, your condescending attitude toward the members of the List perhaps
provoked off track discussion.

In answer to the original question, I'm quite sure that you are very much
aware that the binding affinity of any specific formulation of neonic
depends upon the molecular structures of both the ligand and the receptor
site.  This is how the next generation of neonics is being developed to
target specific insect orders, rather than insects generically.

The answer to your question seems obvious--resistance develops (as it
quickly did with the Colorado Potato Beetle, which was already preadapted
for resistance to alkaloids) by allelic or epigenetic tweaking of the
molecular structure of the receptor site.


-- 
Randy Oliver
Grass Valley, CA
www.ScientificBeekeeping.com

             ***********************************************
The BEE-L mailing list is powered by L-Soft's renowned
LISTSERV(R) list management software.  For more information, go to:
http://www.lsoft.com/LISTSERV-powered.html