One of the varroa reduction methods I use, where appropriate, is to make an 
 artificial swarm then remove the first sealed brood of both parent and 
daughter  colony.  Then there is the usual range of choices as to what to do 
with the  2 colonies: re-unite, leave as 2, make nucs etc.  Apart from your 
time, the  only cost is 2 frames of brood and there are no chemicals involved.
 
It's not the complete answer but part of my IPM.
 
Chris

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