h/t by the "Head of the Enemies" who just received an Award for his
Anit-GMO fight using beekeeping in his favoour

http://igtrcn.org/transgenic-honeybees-finally/

Genome modification technologies have been increasing steadily in recent
years. With the exception of direct genome editing technologies (ZFNs,
TALENs and CRISPRs) variously technologies for use in insects rely heavily
on transposon platforms to move these technologies into target genomes. For
example, phiC31 and other site-specific systems use transposons to move
recombination sites into the target genome. Of course, there is also a lot
of interest in just moving transgenes into insect genomes.

It has been clear for some time that we have available a robust collection
of transposon-based integration systems that have very wide host ranges.
Integration systems are not limiting the use of genome modification
technologies in insects.

What limits the utility of integration systems is insects is delivering
them to germ-line stem cells. To date the only approach that has been
effective has been direct injection of appropriately aged insect embryos.
Of course, post injection survival of those injected insects, maintenance
of their fertility and their successful backcrossing are equally essential.

The use of genome modification technologies in the honeybee, *Apis
mellifera*, are a great case in point.

... more follows.

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