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Informed Discussion of Beekeeping Issues and Bee Biology

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Subject:
From:
"Dr. Thomas Wiese" <[log in to unmask]>
Reply To:
Informed Discussion of Beekeeping Issues and Bee Biology <[log in to unmask]>
Date:
Thu, 20 Aug 2009 17:19:02 -0500
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Smelling acetone on breath is indicative of the body producing ketone 
bodies from the oxidation of fatty acids, so it isn't related to the 
Krebs cycle per se, at least directly.  The enzymes of the Krebs cycle 
are conserved across the animal kingdom.  There may be a difference in 
flux through the pathway in bees compared to a vertebrate, but I would 
be skeptical.  The ketone bodies are produced in starvation and 
diabetes, when the amount of acetyl CoA is greater than the flux through 
the Krebs cycle.  In humans calcium released during muscle contraction 
stimulates flux through the pathway, and though I am a mammalian 
biochemist my instinct is the same would be true with contraction 
associated with beating wings in bees.

------------------------------------------------------------------------
Sincerely,

Dr. Thomas J. Wiese
Professor of Chemistry
415 Lyman, TH351
Fort Hays State University
Hays, KS 67601
(785) 628-4505
E-mail: [log in to unmask]

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