Re: Hot Spots
The authors seem to think that there are "cold spots" in honey bee recombination, but:
Outside of centromeric regions, recombination occurs at high frequencies along all chromosomes. There is currently no evidence that recombination events consistently occur in the same regions along a chromosome (hot spots) within the honey bee genome. The probability of a crossover event increases as the distance from the centromere increases. In sum, clone chromosomes are expected to retain heterozygosity near the centromere and be increasingly homozygous towards the telomere. -- Smith, Nicholas MA, et al. (2019)
Peter L Borst
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