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Date: | Thu, 1 Apr 2021 07:42:55 -0600 |
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The concept of hitting a contagious/infective/parasitic biological
agent early and frequently overlooks a number of biological realities.
Biological systems are not as simple as physical and chemical
relationships where a discrete cause or action produces the same effect
invariably and perpetually. The documented failures of widespread
applications of insecticides, herbicides and even fungicides in
agricultural settings, and the loss of activity of antibiotics in
medical applications point to the fallacy of equating biology with
chemistry or physics.
In beekeeping there are clear examples of the failures of products once
bacteria and mites evolve resistance. One can question the names,
acronyms, buzzwords and fads of corrective proposals, but the failures
are real and have had their economic impact. It is an eye opener to
look into collapsing colonies where a strip with a given active
ingredient has bees walking on it with live mites crawling on them.
Some appear to be counting on the mode of action of some of the current
compounds (like amitraz or oxalic) to be more consistent and long term
in effectiveness. Is there any good background on mode of action or
development of resistance to back up these expectations?
Using extremely low action thresholds for treatment has had documented
failures in many settings and is the setup for rapid loss of
effectiveness of a control product. Unless it has some unique
properties that the target organism will never develop resistance to.
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