Haven't tried it myself, but are you referring to dribble or vapor or
both?  I've read about quite a few people recommending doing 3 rounds of
vapor a week apart to catch a whole brood cycle.  


I have tried it ,  (Vapors usually)  and yes 3 rounds. No queen mortality.

I don't recommend it though as the efficacy rate while there is brood
appears to only be around 60-70%  For a hive in trouble its okay,  but don't
fool yourself into thinking problem solved.   

OA when no brood is present does appear to be way above 90%.

Charles

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