Mite Bomb -- I don't see a need to draw a line in the sand. 
Personally, I know of only one situation where I believe a mite bomb concept could be the only plausible action. To paraphrase a friend's mite harvesting project -- a friend had a yard spinning out of control this past fall, since the hives were terminal he decided to experiment using the sequential ox vapor procedure. Let's just say he grossly exceeded any and all recommendations for repetitions - week after week. Heavy drops, week after week after week after week after week and more. - how can this be possible ? Eventually the drops subsided and the last that I heard, the colonies had weathered the ordeal. He was aware of a neglected group of hives in the vicinity. I was not standing on location but he is quite convinced of the mite bomb theory - a very experienced beek, I might add.

The term mite bomb may replace CCD as a "go to" cause of a colonies demise. Not so long ago, if a colony fell off the transport truck, CCD was to blame. (in the press's eye)

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