> The easy questions have been answered. When a field of science is brand new, all experiments are novel and all results are interesting. It’s in trying to address unresolved problems in old fields that the real challenge begins. Unfortunately, humans are creatures of habit and tend to think of the same ideas and approaches over and over again. When you’ve been in a field for a while, it is harder to think your way out of the box.
> 
> Boning up on other areas of science as a way to generate new ideas in your own field is also a good idea in theory, but the current explosion of knowledge in almost every field of modern biology makes its implementation almost impossible. Most scientists have a hard enough time keeping up with new work in their own subject, much less trying to understand what other scientists are doing.
> 
> Collaborating with researchers who are investigating problems from a different data or analytical perspective is the best way I know to kick-start research creativity.  Such collaborators not only can provide new data, but they also bring their expertise on how to get the most "flavor" out of the ingredient that they contribute to your problem. As the complexity of the important biological problems continues to grow, joining forces to concoct 'fusion cuisines" will become a hallmark of the most creative research, giving lie to the old saw that too many cooks spoil the broth.

Quoted for review purposes only from 
Cooking Up Creative Solutions: More collaborators and more data are the key ingredients.
By H. Steven Wiley | May 1, 2012 | the-scientist.com
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