From Eric Mussen's Letter...

...it is 
interesting to note what Zachary Huang’s 
lab discovered (ABJ abstract #14) about 
feeding fumagillin to honey bees to control 
Nosema ceranae.  In their studies, they 
found that the antibiotic impacts both the 
parasite and the protein makeup of the 
honey bee intestinal tract.  In fact, as the 
level of fumagillin decreases in the bees 
over time, it reaches a low level which 
actually stimulates spore production of N. 
ceranae.  A similar effect is seen with N. 
apis, but it is not nearly so pronounced.  It 
could be that the low levels of fumagillin 
may be suppressing the honey bee immune 
system.  The use of fumagillin as a last 
resort cancer treatment in mammals severely 
impairs their immune system. 

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