From Drosophila Models of Proteinopathies: the Little Fly that Could
Diego E. Rincon-Limas, Kurt Jensen and Pedro Fernandez-Funez*
4.5. Prion Diseases
Prion diseases (PrD) are unique among the protein misfolding
disorders because they can present with sporadic, genetic, and in-
fectious etiologies. These neurodegenerative disorders affect hu-
mans and other mammals and lead to dementia, motor dysfunction,
and, eventually, death
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