A must-read article!

<snip>
> ...He chose to publish one paper, fittingly, in the online journal PLoS Medicine, which is committed to running any methodologically sound article without regard to how “interesting” the results may be. In the paper, Ioannidis laid out a detailed mathematical proof that, assuming modest levels of researcher bias, typically imperfect research techniques, and the well-known tendency to focus on exciting rather than highly plausible theories, researchers will come up with wrong findings most of the time.
<snip>

http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/8269/1/

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