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Date: | Sun, 26 Jul 2009 17:45:15 -0700 |
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>
> >Just as good a case could be made against short term antibiotic use: if
> you use it for a
> week or two in spring, you will kill off the susceptible bacteria, leaving
> only the resistant
> ones.
Pete, 'm not sure that a good case could actually be made. Short-term use
in a portion of an operation utilizes the "refuge strategy" of pest
resistance management. The strategy being that the remaining nonresistant
pest will generally be more fit than the resistant pest (in the absence of
the chemical control agent), and outcompete it once the agent is removed.
With continual use of antibiotic, there is no refuge for nonresistant
strains of bacteria. Therefore, selective pressure would strongly favor any
resistant strains that possess alleles for resistance, or randomly mutate,
or pick up plasmids for resistance, or epigenetically upregulate genes that
confer resistance.
>I have met many people who have successfully stamped out AFB.
I have personally done so a few times over the years (serious spread in the
operation) mostly by burning, plus judicious use of antibiotic in targeted
yards, and when doing "shake and bake."
I haven't used antibiotics prophylactically for a number of years, which is
why I'm curious about Bob's experience with EFB when OTC isn't used. I'm
seeing more EFB-like symptoms, but they don't go away like EFB used to when
a good pollen/nectar flow comes on.
I've been too busy to do a good controlled trial of OTC and tylosin against
the symptoms, but will try to get around to it. So far, either antibiotic
(dusted) appears to help.
Randy Oliver
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