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Hi Anne! Here are a few references for you regarding the use of infant formula and the risk of sensitizing breastfed infants to diabetes.

Goldfarb, M. Relation of Time of Introduction of Cow Milk Protein to an Infant and Risk of Type-1 Diabetes Mellitus Journal of Proteome Research 2008; 7:2165–2167.

Carol S. Johnston, Woodrow C. Monte. Infant formula ingestion is associated with the development of diabetes in the BB/Wor rat  Life Sciences 2000; 66 ;1501-1507 

Åkerblom HK, Virtanen SM, Ilonen J, Savilahti E, Vaarala O, Reunanen A, Teramo K, Hämäläinen AM, Paronen J, Riikjärv MA, Ormisson A, Ludvigsson J, Dosch HM, Hakulinen T, Knip M, the Finnish TRIGR Study Group: Dietary manipulation of beta-cell autoimmunity in infants at increased risk for type 1 diabetes. Diabetologia 48:829–837, 2005

Karjalainen J, Martin JM, Knip M, et al. A bovine albumin peptide as a possible trigger of insulin-dependent diabetes mellitus. N Engl J Med 1992; 327:302-307

Gimeno SG, deSouza JM. IDDM and milk consumption: a case-control study ion Sao Paulo, Brazil. Diabetes Care 1997; 20:1256-1260.
Lempainen J, Vaarala O, Mäkelä M, Veijola R, Simell O, Knip M, Hermann R, Ilonen J.Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes. J Autoimmun. 2009 Sep;33(2):155-64. Epub 2009 May 26.
TRIGR Study Group. Study design of the Trial to Reduce IDDM in the Genetically at Risk (TRIGR). Pediatr Diabetes. 2007 Jun;8(3):117-37.

See if any of these are helpful.

Marsha Walker, RN, IBCLC
Weston, MA


Date:    Sun, 3 Jan 2010 02:16:22 -0500
rom:    Anne Perry <[log in to unmask]>
ubject: question for Marsha-hydrolysed formula
Hi Marsha
an you please tell me where I could find research on the use of hydrolysed 
ormula & reduced risk of diabetes.
f our breastfeeding mums need to give formula & have a history of 
sthma,eczma,hayfever we give a hydrolysed one.
hanks
nne in Oz





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