Received: from md.egroups.com (md.egroups.com [207.138.41.139]) by enterprise.fuse.net (8.8.5/8.8.5) with SMTP id KAA20217 for <[log in to unmask]>; Tue, 13 Apr 1999 10:11:11 -0400 (EDT) Received: from [127.0.0.1] by md.egroups.com with NNFMP; 13 Apr 1999 15:11:05 -0000 Mailing-List: contact [log in to unmask] X-Mailing-List: [log in to unmask] X-URL: http://www.egroups.com/list/armidwives/ Delivered-To: [log in to unmask] Received: (qmail 8358 invoked by uid 7770); 13 Apr 1999 14:10:59 -0000 Received: from imo21.mx.aol.com (198.81.17.65) by vault.egroups.com with SMTP; 13 Apr 1999 14:10:59 -0000 Received: from [log in to unmask] by imo21.mx.aol.com (IMOv20.9) id aWFQa19569 for <[log in to unmask]>; Tue, 13 Apr 1999 10:09:32 -0400 (EDT) From: [log in to unmask] Message-ID: <[log in to unmask]> Date: Tue, 13 Apr 1999 10:09:32 EDT To: [log in to unmask] MIME-Version: 1.0 X-Mailer: AOL for Macintosh sub 189 Reply-To: [log in to unmask] Subject: (ARM) Four year follow-up of neonates having epidurals Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 7bit Here is another study for the interest of the list and to post anywhere: Hollenbeck AR, Grout LA, Smith RF, Scanlon JW. Neonates prenatally exposed to anesthetics: Four-year follow-up. Child Psychiatry and Human Development 1986; 17(1):66-70. Abstract: This brief report provides the four year follow-up on infants prenatally exposed to anesthetics. Fourteen of 39 infants examined at birth were available for intelligence testing at age four. Results indicate that Peabody Picture Vocabulary IQ scores are correlated with visual preference testing at birth in infants exposed to prenatal anesthetics. The mean IQ's of these infants also differed from mean IQ's of unexposed infants at four years. These preliminary data are suggestive of prenatal anesthetic effects that are persistent and that early infant visual screening may be predictive of later IQ. Blair VW, Hollenbeck Ar, Smith RF, Scanlon JW. [Neonatal preference for visual patterns: Modifications by prenatal anesthetic exposure. Developmental Medicine and Child Neurology 1984; 26:476-483.] studied 9 infants who had been exposed to an anesthetic prenatally with 30 unexposed infants, testing for visual pattern preferences. The exposed infants looked at stimuli longer and had different preferences for some pairs of patterns. These same authors documented substantial behavioral effects in rats prenatally exposed to lidocaine and mepivacaine. Looking time at birth was correlated with PPVT Scaled IQ scores at four years (r = -.91, p < .01) for the exposed groupwhile there was no correlation for the unexposed group. After covarying out initial looking differences, there was a significant mean difference in PPVT IQ scores between exposure groups (t = 1.91, d.f. = 12, p <.05, one-tailed). Approximately one standard deviation separated the means of the exposed group (M = 91.33, s.d. = 14.56) and the unexposed group (M = 107.75, s.d. = 19.94). This small study follow-up provides data consistent at four years with the results following birth. The infant group exposed to anesthetic agents continued to show visual performance differences at four years.... What seems remarkable is that even with such a small sample size, a group difference is still detected. ------------------------------------------------------------------------ eGroups eLerts! Exclusive discounts on travel Join Now! http://clickhere.egroups.com/click/24 eGroup home: http://www.eGroups.com/list/armidwives Free Web-based e-mail groups by eGroups.com