I have always asked mothers to wean off the domperidone slowly. I don't know if it makes any difference to stop it suddenly. It might. There is no reason the mother cannot use blessed thistle and fenugreek and domperidone all at once. That might ease the weaning off from the domperidone. I doubt anyone has done any study on this issue. It would be very complex to do it. Jack Newman, MD, FRCPC