RE: Methylprednisolone The amount that an infant would ingest in a day on average is 0.5%. Data from a patient suggests that the risk to the infant is low based on the quantity of the drug that passes into milk is small. A general recommendation is that it is best to dose the drug at less than 8mg/day, but with this short-term, descending dosing schedule, there should be no need for any weaning. As for the Percocet, I do not understand what is bad for the baby when the mother takes Percocet and methylprednisolone. In addition, why is Percocet prescribed so often for nursing mothers when plain Tylenol or possibly Tylenol with Codeine would be a much better choice if an analgesic is needed? Frank J. Nice, DPA, CPHP