There was a recent article in a journal hereabouts. It was in what we call a "throwaway journal". A "throwaway journal" comes free, its purpose is drug advertising with articles as a come on, though of course, nothing previously mentioned means the articles can't be quite good. I threw it away, unfortunately, so I can't be more specific than what I've written below. Anyhow, the person writing basically said that nobody really knows what works with St. John's wort, though they had a few ideas. He also said that the concentration of MAO inhibitor in it (the drug with which you have to be careful what you eat and all that) was so low, that it was not a concern. Jack Newman, MD, FRCPC