Asacol is a drug used in inflammatory bowel disease (Crohn's disease and ulcerative colitis). It is one of a class of drugs used in this disease called ASA derivatives which also includes azulfadine (sulfasalazine), pentasa, and dipentum. Azulfadine, the oldest of these drugs has been used safely in pregnancy and breast feeding for many years. Asacol, which is similar to azulfadine (except that the sulfa portion is absent), is VERY LIKELY safe in breast feeding moms and I have personally recommended it in these circumstances. My question in this case is: Does this mom have proven inflammatory bowel disease? I wouldn't recommend just "trying" this drug without proof of disease. Peter Salomon,MD, FACG Board Certified Gastroenterologist Boca Raton, FL