I may be the only person who ever inquires on this drug, but just in case I'm not, I am posting Tom Hale's response to my inquiry concerning Fosomax to the list: --------------------------------------- "Fosamax is an aminobisphosphonate that selectively blocks calcium reabsorption by the osteoclast. Basically, bone is under constant restoration and destruction throughout life. This drug blocks the breakdown and release of calcium by the osteoclast. The product literature says that it is secreted into human milk and should not be used in lactating women. Fosamax has strange kinetics, it is very poorly absorbed, only 0.7% of the oral dose is absorbed. It rapidly distributes out of the plasma compartment and deposits in bone. The bone terminal half-life is 10 years (yes, years). My greatest concern is that a child's bones are constantly undergoing change, including breakdown, and rebuilding in a different shape as the body grows. We have no understanding as to how this product would alter the skeletal structure if used in early pediatrics. Further, once its in there, it would take years to get rid of it. This is one of those occassions that I would recommend not breastfeeding. The risk to the infant may to be too high, we simply don't know."