Rosa: "secreted into milk in varying amounts which approach maternal serum levels. actual concentrations contraersial. levels may ( but probably not) be sufficient to prevent withdrawal in nursing infant. one death reported. considered compatible with breastfeeding under contrained conditions. aap approves if maternal does of methadon is less than 20/mg/24hrs. use extreme caution. monitor for sedation, constipation, agitation or withdrawal. aap compatable...." p218-219 patricia