I too have used underwire bras, nursed all 4 of my kids, but would have to say that I have had some trouble with them. The worst offenders for me were the nursing bras with underwires, when I would open them from the top my breast was being still held or cupped underneath by the bra and this pinched the tissue enough to cause congestion and inflamation, so I went to a standard bra and slip it over the breast no pinched tissue. The other times I had trouble were sleeping with the bra on, the underwire put too much pressure on the glans on the side , swelling & pain was under the arm pit and a little forward, and last but not least poor fitting bras in general have caused me trouble in the past. Sharon DEM, Tucson,Az.