Denise, It sounds like you have been doing all of the best things, but not all at once; you might consider adding lotrimon for the nipples and continuing nystatin orally for baby's mouth *in conjunction with* the fluconazole therapy. Or, as an alternative, the gentian violet along with the diflucan. Sometimes you have to hit inside and out simultaneously; the systemic drug doesn't always knock out the outer infections. Your mom sure has a bad case, poor thing! Along with your dietary limits, she could also consider adding garlic capsules (kyolic makes an odorless one) and lactobacillus or acidophilus to help fight the yeast and replenish the good bacteria. I assume you have also gone through the transmissible objects --- pacifiers, bottles, toys, pads, bras, etc. and recommended sterilization? It's a pain, but when you have a stubborn case, you don't want to leave any stone unturned. Good idea to culture the milk and have mom checked for anything else. Let us know how this one goes! -Lisa Marasco, IBCLC [log in to unmask] / [log in to unmask]