Arly's point, about an allergic reaction, is a good one. My midwife and I went through the whole list: different spermicide (no) different detergent (no) new underwear (no) change in diet (no) --- nothing seemed to fit. I realize that it's possible to develop an allergic reaction to something that has previously been OK but it doesn't seem as plausible, and the fact that I didn't develop symptoms when I used the monistat cream immediately post-coitally would seem to strengthen my suspicions. I don't normally like the "practice" (apt word) of medicine that says, "Let's take this, and see if it works - then we'll know what we have!" but it DID help in this instance! Mary R, wondering what my husband would think if he knew this discussion was taking place????