OK, I finally decided to put my 2 cents in about prozac...not only is it popular in California--I worked for 5 years in LA-I have just as many people requesting it in a semirural town in WI where I am now!! I agree with Dr. Hale...blood levels being low and having the baby appear to be healthy unfortunately can not tell the future of a medication effect..look at DES for example. The children of women who took DES during their pregnancy were found to have problems as adults, and we are still screening these women born 2 decades ago. I guess I worry about psychactive drugs in general, and whether these kids are going to be at increased risk for depression or some other neurotransmitter-related pathology in the future. I have given prozac to nursing moms...but it makes me sweat, and more recently I have been asking breastfeeding supportive psychiatrists to make the call for me, on whether the woman truly needs antidepressants. If the woman cannot afford a psych eval, I try to consider the use of imipramine first.-Anne Eglash MD