Hi Lisa, ...to update others re the vasospasm issue, I have one mom who was not responding well to nifedipine extended release , 60mg ; I was having her take it at nite, though it is extended release and lasts 12-24 hours. She wasn't getting better, and then I realized she needs to take it in the am, and she is doing much better. The rheumatologist has even found that with his Raynaud's patients they sometimes need to take the extended release nifedipine 2-3 times a day...actually I have noticed some cardiologists doing this too for hypertensives. I have discussed nipple vasospasm with 2 rheumatologists recently, and both have been in practice for several years, neither were familiar with this phenomenon of the nipples, though they both agreed it made sense with the symptoms described! They both also say that they know of no other allopathic meds that work well for Raynauds, and a good peripheral vasodilator is greatly needed in their field.-Anne Eglash MD