I first took Reglan in 1991, while waiting for my daughter to be placed for adoption. After three weeks, I got off of it and had severe depression, as a result. Since I had felt that it did increase my milk production, I tried to take it on several other occasions, hoping to find something to do differently which would make it tolerable. Each time, I saw some increase in production, but ended up too depressed to function and, each time, my milk production dropped to what it had been before. We have seen many adoptive moms who have used it, in the past, very few of whom have not decided to get off of it, due to depression, anxiety, or at least sedation, which made it difficult for them to function. Some have had trouble with depression otherwise, and some have not. Most have not stayed on it very long, and have had the symptoms go away fairly soon after they stopped taking it. However, the longer one has been taking it, the longer it tends to take to get rid of the symptoms. One of the most severe cases I know about was someone who'd never had clinical depression at all before, but had one heck of a time getting rid of it after many months on Reglan. It took her a good six months under a psychiatrist's care to make a significant improvement. The most severe case I know of was someone who had a history of clinical depression, but no where near as severe as what she experienced from Reglan. The poor woman ended up spending time in a psych ward, because she had tried to commit suicide, while other people bottle fed her baby. She had been on Reglan for months, and had asked her doctor if the increasing difficulty she was having could have been from it, and was assured that it wasn't! Not only did this woman not succeed at breastfeeding her adopted baby, she wished she had never even heard of it! There have been claims made about how long it should or shouldn't be used. In 1990, it was being claimed that depression was rare if it was taken for less than two months. The same source also claimed such things as that some women could take it for very long periods without depression and then be hit with it later, and also that, when women stopped taking it, the symptoms would go away quickly. From what I have seen, none of that is correct. There are also other concerns about Reglan, and I have heard of at least one class-action suit against the manufacturers. There is one physician I know of who has been advising staying on it for no longer than two weeks, to lessen the chances of side-effects. Overall, I think it is best to stay away from it, for milk production. It is SUCH a shame that Americans are more comfortable with it than domperidone, and that we can't get it here, when the latter is both safer AND more effective. For those who don't want to try dom, I would try other things first. It also depends on how much the milk supply needs to be augmented. I haven't seen anyone who had a huge increase in milk production from Reglan. In cases where it might make the difference between a baby getting 100% breastmilk and needing some formula, it might be worth taking a bit more of a risk of adverse effects than if, like in many adoptive cases, it increased the amount of breastmilk, but there was still a considerable amount of formula needed. I have another thought. Since Reglan has such an immediate response, perhaps it could be used as the first step in some cases, with other things being taken on at the same time (herbs, dom, etc.) and then the Reglan stopped when the other things would be likely to have kicked in. Has anyone tried that? Darillyn *********************************************** To temporarily stop your subscription: set lactnet nomail To start it again: set lactnet mail (or digest) To unsubscribe: unsubscribe lactnet All commands go to [log in to unmask] The LACTNET mailing list is powered by L-Soft's renowned LISTSERV(R) list management software together with L-Soft's LSMTP(R) mailer for lightning fast mail delivery. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html