Carissa, Prednisone is a steroid and can definitely predispose someone to a yeast infection-- that is a classic risk factor. Steroids suppress the immune system, and in doing so interfere with the body's ability to balance yeast and bacterias. The steroid will clear her system pretty quickly, but that probably isn't going to solve the problem now that yeast overgrowth has taken hold. If she is having nipple or breast yeast, that needs to be treated along with any other break-out sites. If it is really entrenched, diflucan might help her get over the hump more quickly. I usually recommend that topical treatments be continued for a week past the cessation of all symptoms. In addition, if mom does indeed have nipple yeast, baby should probably be treated to avoid re-infection. Lisa Marasco LLL MA IBCLC *********************************************** The LACTNET mailing list is powered by L-Soft's renowned LISTSERV(R) list management software together with L-Soft's LSMTP(TM) mailer for lightning fast mail delivery. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html