Dear friends,

I hope some of you can shed some light on a debate that is going on between
some Dutch LC's.  Some are very sure that fluconazole can be a contributing
factor to vasospasm of the nipple, others are of the opinion that vasospasm
may be a complication of the thrush that is treated with fluconazole (pain
may trigger vasospasm).
As statet by a Dutch representative of the manufacturer of fluconazole
(Pfizer) vasospasme is not known to be a complication of fluconazole-use and
Hale does not list it as complication. Pfizer states the if vasospasm is a
complication of fluconazole it should appear in all extremities and not just
in the nipple.
In the LC literature is not much to find. Lawrence 4th ed, Riordan & Auerbach
and the BAB do not index vasospasm at all. Core Curriculum (Walker) does
mention vasospasme, but no link with fluconazole and Barbara Wilson Clay (bf
atlas) has 1 line that links vasospasm to fluconazole.
So is this link between fluconazole and vasospasm of the nipple proven (and
where/when) and if so is the link pointing towards fluconazole as cause or
are they both just there at the sam time?

Warmly greeting,

Gonneke
==================
Gonneke van Veldhuizen  =+=  IBCLC, LLLL, MOM  =+=  primairy school teacher

EUROLAC
breastfeeding information centre and lactation consultant practice
http://www.users.skynet.be/eurolac




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