Dear friends, I hope some of you can shed some light on a debate that is going on between some Dutch LC's. Some are very sure that fluconazole can be a contributing factor to vasospasm of the nipple, others are of the opinion that vasospasm may be a complication of the thrush that is treated with fluconazole (pain may trigger vasospasm). As statet by a Dutch representative of the manufacturer of fluconazole (Pfizer) vasospasme is not known to be a complication of fluconazole-use and Hale does not list it as complication. Pfizer states the if vasospasm is a complication of fluconazole it should appear in all extremities and not just in the nipple. In the LC literature is not much to find. Lawrence 4th ed, Riordan & Auerbach and the BAB do not index vasospasm at all. Core Curriculum (Walker) does mention vasospasme, but no link with fluconazole and Barbara Wilson Clay (bf atlas) has 1 line that links vasospasm to fluconazole. So is this link between fluconazole and vasospasm of the nipple proven (and where/when) and if so is the link pointing towards fluconazole as cause or are they both just there at the sam time? Warmly greeting, Gonneke ================== Gonneke van Veldhuizen =+= IBCLC, LLLL, MOM =+= primairy school teacher EUROLAC breastfeeding information centre and lactation consultant practice http://www.users.skynet.be/eurolac *********************************************** The LACTNET mailing list is powered by L-Soft's renowned LISTSERV(R) list management software together with L-Soft's LSMTP(TM) mailer for lightning fast mail delivery. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html