Holly, The answer to your question is, "yes, most likely." My first thought was of how this woman's hyperprolactinemia was treated-- probably with bromocriptine. I wonder how long the treatment lasted. You mention that her prolactin levels were "normal" after the first pregnancy. Do you know what the levels were, and exactly when postpartum? Also, did she experience pregnancy breast growth? Veining? I would also be interested in knowing upon what basis this mom might have PCOS. What other aberrant hormones has she had, or clinical symptoms? Other hormones I would be most interested in include testosterone, progesterone, and thyroid, along with insulin and insulin resistance. My research suggests that some hormonal issues can cause more subtle problems such as downregulation of prolactin receptors. In such cases, prolactin levels can be "normal," yet little response from the breast. I would expect that women in these situations may have decent pubertal breast growth, but mild pregnancy growth. I will be interested in your answers to the above questions. In the meantime, I am favoring Goat's Rue for moms in these situations, though I don't have much experience with it yet (other lactnetters do). Lisa Marasco IBCLC *********************************************** The LACTNET mailing list is powered by L-Soft's renowned LISTSERV(R) list management software together with L-Soft's LSMTP(TM) mailer for lightning fast mail delivery. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html