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Subject:
From:
"Catherine Watson Genna, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 23 Dec 2004 19:19:23 -0500
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Found this interesting study while searching out new articles on sucking 
behaviors!

*Method for hand-feeding mouse pups with nursing bottles.*

Hoshiba J.

/Contemp Top Lab Anim Sci/. 2004 May;43(3):50-3.

Department of Animal Resources, Advanced Science Research Center, 
Okayama University, 2-5-1, Shikatacho, Okayama, 700-8558, Japan.

The purpose of this study was to establish a hand-feeding method for the 
mouse by using nursing bottles. Five different-sized nipples were 
tested. The largest nipple used for pups from 12 to 15 days of age was 
5.5 mm in diameter and 10 mm long, with a tip of 1.5 mm in diameter. The 
size of the nipple was much larger than that of the mothers, and 
bloating due to air accumulation was observed in the artificially-reared 
pups. To prevent bloat, the nipple size was increased, and a piece of 
sponge was stuffed in the nipple. Among the 30 pups fed from 1 day of 
age, 26 were weaned and 4 died. Three pups died due to aspiration of 
milk into the lung, and the remaining one died due to bloating. The 
development of nursing bottles with nipples may be potentially useful 
for the studies of nutrition, behavior, immunology, psychology, and 
toxicology.

Catherine Watson Genna, IBCLC  NYC

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