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Subject:
Re: Medications
From:
Glenn Evans <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 17 Mar 1997 20:37:42 -0800
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From Tom Hale, his post to the net on February 20, re paroxetine (Paxil):

"A short letter to the editor last month reviews the breast milk level of paroxetine (paxil) in one patient at steady state.  Source = Spigset et.al., J. Clin Psy. 57:1, p. 39, 1996.

"The concentration of paroxetine in milk, obtained 4 hours after the dose (20 mg. day) was 23 nmol/L(7.6 ug/l).  This is a milk:plasma ratio of about 0.09.  Daily dose to infant would be approximately 1.14 ug/Kg body weight, or about 0.34% of the maternal dose, exceptionally low."

Chanita, San Francisco

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