@#$%&($%#
This isn't working out. I had no idea the number of people who would reply
to my "alarming study" post. Right after I posted I realized, I have no
way of knowing if the persons replying are legit!
List mothers, is it possible to screen Lactnet members for those who have a
true reason to be here? I will volunteer to help, if you think it's
doable. Perhaps verify with IBCLE, LLL, etc.?
In any case, I'm just going to go ahead and post it right here and hope for
the best. The *s indicate a significant point.
My concern is that, if they are not already aware of them, the formula
companies will attempt to capitalize on this information. I am beginning
to become suspicious of these studies, I do not have access to the full
articles to see if conflicting interests are stated, but… those of you who
do, will you please let me know? I have this paranoid idea that “they” are
funding self-serving studies slanted their way.
Science of The Total Environment
Volume 329, Issues 1-3 , 15 August 2004, Pages 289-293
Copyright © 2004 Elsevier B.V. All rights reserved.
Short communication
Organochlorine compounds in breast-fed vs. bottle-fed infants: preliminary
results at six weeks of age
G. -M. Lackmann, , a, K. -H. Schallerb and J. Angererb
a Outpatient Paediatric Office, Reinstorfweg 10a, 21107, Hamburg, Germany
b Institute of Environmental Medicine, Friedrich-Alexander University,
91054, Erlangen, Germany
Received 4 June 2003; Revised 6 February 2004; accepted 17 March 2004.
Available online 25 May 2004.
Abstract
Background: Polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), and
1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) are ubiquitous
compounds with carcinogenic and teratogenic properties. They are chemically
very stable and lipophilic and, therefore, accumulate in our food-chain.
They are prenatally transmitted from mother to foetus, and mother's milk
due to its high lipid content is an elimination pathway of special
importance. Therefore, breast-feeding has been held responsible for
elevated concentrations of these organochlorine compounds as well as for
harmful effects in children later in life. Methods: Blood samples (2.5 ml)
were taken from each 10 breast-fed and bottle-fed infants at 6 weeks of
age. Blood specimens were immediately centrifuged, and serum was stored in
glass tubes at −20 °C until analysis. Three higher chlorinated PCB
congeners (IUPAC nos. 138, 153 and 180), HCB, and the organic metabolite of
DDT, p,p<<-DDE, were analysed with capillary gas chromatography with
electron capture detection. Reliability was tested with gas chromatography-
mass spectrometry. Results: There were no differences between the study
groups of breast-fed and bottle-fed infants with regard to sex
distribution, gestational age, birth-weight, age of the mothers, and
smoking behaviour of the parents. In contrast, serum concentrations of all
organochlorine compounds were significantly higher (P<0.0001) in breast-fed
than in bottle-fed infants (mean): PCB 138, 0.38 vs. 0.10 g/l; PCB 153,
0.49 vs. 0.1 g/l; PCB 180, 0.31 vs. 0.04 g/l; PCB, 1.19 vs. 0.29 g/l; HCB,
0.13 vs. 0.04 g/l; p,p<<-DDE, 1.05 vs. 0.18 g/l. Conclusions: Breast-
feeding significantly increases the pollution of our infants with different
organochlorine compounds as early as at 6 weeks of age. *********The
progress of the present study will show whether this pollution will further
increase with longer duration of breast-feeding, and whether breast-feeding
bears any health risks for our offspring. **********
Author Keywords: Organochlorine compounds; Breast-feeding; Environmental
pollution; Polychlorinated biphenyls; Hexachlorobenzene; 1,1,1-trichloro-
2,2-bis(p-chlorophenyl)ethane

Corresponding author. Tel.: +49-40-758811; fax: +49-40-63702231
Am J Epidemiol. 2004 Aug 1;160(3):217-23.
Breastfeeding and risk of atopic dermatitis, by parental history of
allergy, during the first 18 months of life.
Stabell Benn C, Wohlfahrt J, Aaby P, Westergaard T, Benfeldt E, Fleischer
Michaelsen K, Bjorksten B, Melbye M.
Department of Epidemiology Research, Danish Epidemiology Science Centre,
Statens Serum Institut, Copenhagen, Denmark. [log in to unmask]
The role of breastfeeding in allergic diseases remains controversial. The
authors studied the association between breastfeeding and development of
atopic dermatitis during the first 18 months of life among children with
and without a parental history of allergy. A cohort study of 15,430 mother-
child pairs enrolled in The Danish National Birth Cohort was carried out
between 1998 and 2000. Data on breastfeeding, atopic dermatitis, and
potential confounders was obtained from telephone interviews conducted
during pregnancy and when the children were 6 and 18 months of age. The
cumulative incidence of atopic dermatitis was 11.5% at 18 months of age.
Overall, current breastfeeding was not associated with atopic dermatitis
(incidence rate ratio (IRR) = 0.91, 95% confidence interval (CI): 0.80,
1.04). Exclusive breastfeeding for at least 4 months was associated with an
*******increased risk *******of atopic dermatitis in children with no
parents with allergies (IRR = 1.29, 95% CI: 1.06, 1.55) but not for
children with one (IRR = 1.11, 95% CI: 0.94, 1.31) or two (IRR = 0.88, 95%
CI: 0.69, 1.13) parents with allergies (test for homogeneity, p = 0.03).
The authors found no overall effects of exclusive or partial breastfeeding
on the risk of atopic dermatitis. However, the effect of exclusive
breastfeeding for 4 months or more depended on parental history of allergic
diseases.
PMID: 15257994 [PubMed - indexed for MEDLINE]
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