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Lactation Information and Discussion <[log in to unmask]>
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Wed, 4 Aug 1999 16:44:00 EDT
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http://www.medscape.com/Medscape/features/JournalScan/WomensHealth/1999/js-wh0
207.html

From Obstetrics & Gynecology
July 1999 (Volume 94, Number 1)

Bone Mineral Changes During and After Lactation
Polatti F, Capuzzo E, Viazzo F, et al.
Obstet Gynecol 94(1):52-56, July 1999
The extent of calcium loss that occurs during lactation is related to the
amount of breast milk produced, diet, and duration of lactation.
Hypoestrogenemia occurs during lactation and adversely affects calcium and
phosphate metabolism. The return of ovarian function varies among women,
resulting in large differences in bone loss and bone mass. Polatti and
colleagues investigated the variation in bone loss among lactating women.

Three hundred eight lactating women committed to breastfeeding for 6 months
and weaning for 1 month. Of these, 274 fulfilled the commitment and were
included in the study. Cabergoline was administered at 7 months to all women.
One hundred thirty-five were assigned to group 1 (lactating without calcium
supplementation), and 139 to group 2 (lactating with calcium
supplementation). The control group comprised 153 nonlactating women. Radius
and spine bone mineral density were measured immediately postpartum and 3, 6,
and 12 or 18 months after delivery.

A significant decrease in bone mineral density occurred up to 6 months, with
improvements found thereafter. After 18 months, bone mineral density values
were improved from early postpartum in all three groups.

Related articles:
-- Osteoporosis Risk Factors, Screening, and Treatment
-- Heterogeneity of Bone Mineral Density Across Skeletal Sites and Its
Clinical Implications
-- Osteoporosis: Assessing and Using Risk Factors for Fracture

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