Don't breastfeed in the 5 minutes immediately following the dose???
seriously tho, I would think not breastfeeding for 12-24 hours will be
plenty of time.  It is given as a single dose or an infusion over several
hours.  Monitor baby's PT & PTT, platelets if there is any concern, observe
for any bleeding, bruising - same as for mom.  Sincerely, Pat in SNJ

> "It is not known whether alteplase (t-PA) crosses into human milk. Because
> of the nature of the indications for this agent and its very short initial
> half-life (less than 5 minutes), the opportunities for its use during
> lactation or the possibility of exposure to a nursing infant are minimal."

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