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Lactation Information and Discussion <[log in to unmask]>
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Mon, 27 Oct 1997 17:40:25 -0500
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Here is what the Canadian equivalent of the PDR says about 
metronidazole:

Metronidazole has been cited as a drug contraindicated during 
lactation.  This advice is based on reports that the drug is mutagenic 
in bacteria and carcinogenic in rodents when taken throughout their 
lives.  Specific untoward effects in a nursing infant as a result of 
metronidazole ingestion have not been reported.  Without more direct 
evidence of the harmful effects of short term use in humans it seems 
overly conservative to withhold the drug or discontinue breastfeeding 
in patients with symptomatic parasitic diseases (amebiasis, giardiasis 
or trichomoniasis) for which metronidazole may be the treatment of 
choice.

‹Drug Exposure During Lactation. Compendium of Pharmaceutical 
Specialities. 1997. page L36.

The issue is, once again, does a small amount of metronidazole in the 
milk render breastfeeding more hazardous than formula?  The answer, in 
my book is patently no, and breastfeeding is *still* better for mother 
and baby.

Jack Newman, MD, FRCPC

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