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Subject:
From:
Cathy Fetherston <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 21 Oct 2001 15:13:40 +0800
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The  original papers first identifying the link to autocrine control in
women are:

Daly SD & Hartmann PE. 1995 Infant demand and milk production (part 1) & The
short term control of milk synthesis (part 2)  in Lactating women. JHL 11:
21-37.

Cox, DB., Owens RA & Hartmann PE. 1996. Blood and milk prolactin and the
rate of milk synthesis in women. Experimental Physiology. 81. 1007-20.

Daly, SE Kent JC Owens RA & Hartmann PE. 1996. Frequency and degree of milk
removal and the short term control of milk synthesis. Experimental
Physiology. 81 861-875.

There is however a nice review of this work and others in JHL by
Cregan & Hartmann 1999 Computerised breast Measurement from conception to
weaning: clinical Implications. JHL 15(2) 89-96.

There isn't anything really showing "a shift" from endocrine to autocrine
control - its probable that they work together - with prolactin, appearing
at this time from the evidence, to have a permissive role while the
autocrine control is responsible for amount of milk produced. The autocrine
influence appears to come into play when Lactogenesis II begins.

Regards
Cathy Fetherston
Perth Western Australia

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