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Subject:
From:
Cathy Kaiser <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 3 Jun 1996 08:27:47 -0400
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Cynanne:

I just downloaded some information about Tegretol this weekend from the
internet for my mom:

"Lactation:  Carbamazepine (Tegretol) passes into breast milk in
concentrations of about 25 to 60% of the plasma level.  No reports are
available on the long-term effect of breastfeeding.  The benefits of
breastfeeding should be weighed against the possible risks to the infant.
 Should the mother taking carbamazepine nurse her infant, the infant must be
observed for possible adverse reactions, e.g. somnolence.  A severe
hypersensitivity skin reaction in a breastfed baby has been reported."

And from Tom Hale's book:
"Generic = CARBAMAZEPINE.  Anticonvulsant.  Small amounts secreted (2.3 mg/L
milk).  Levels in infant are generally less than 1 mg/ml plasma, and have not
been found to produce toxicity in infant.  Accumulation does not seem to
occur.  Compatible in nursing mothers, with observation.  Observe infant for
sedation.  AHL = 18-54 hrs.  PB = 74%  PHL = 8-28 hrs.  AAP Compatible with
breastfeeding"

Cathy Kaiser
[log in to unmask]
Franklin, TN

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